FIRST PRESCRIPTION
Most people have never heard this part: when a back flare or a fresh back injury gets a first opioid prescription, the odds of still being on opioids months later rise with every extra day in that first supply. For most flares, ibuprofen with acetaminophen, TENS, vibration and steady movement come first. Some backs need more for a short time.
I am writing this on a broken left leg, so let me explain why a back pain site is hearing from me about it.
Why is a doctor with a broken ankle writing about back pain?
On October 11, 2026, a little before 6 a.m., I stopped on the highway to get a woman out of a burning car. While I was moving her to the shoulder, a hit-and-run driver struck me. She did well. I ended up with a medial malleolus fracture and a fibula fracture in my left leg, an ankle cut of about 15 centimeters that tore the tibial artery, roughly 40% of my blood volume gone, a trauma team activation and two broken ribs. No surgery was needed, and the wound was closed.
I have kept working, though I cannot stand long enough yet to do my full load of procedures. Update, October 26: I hit that target. Full function is back, and so is my full procedure load.
In the ER I was offered opioids again and again, and I declined every time. The reason I declined is the same reason this matters for your back.
How does one opioid prescription for back pain turn into years?
Almost nobody with a bad back sets out to take opioids long term. It starts on a Tuesday when you bend for a laundry basket and cannot straighten up. You get a prescription that seems perfectly sensible. Then the flare lasts longer than the bottle, and there is a refill.
That sequence is exactly what the data flags. In commercially insured adults with no cancer and no recent opioid use, the CDC found that the probability of long-term use rose with each day of opioids supplied in the first episode. The steepest increases followed day five and day thirty-one, once a second prescription or refill was added, when the cumulative dose reached 700 morphine milligram equivalents, and when the first prescription was written for 10 or 30 days.1
So the size of the first script is not a detail. It is the lever. A three-day supply and a thirty-day supply for the same flare are not the same decision.
Are some back pain patients at higher risk from a first prescription?
Yes, and the risk sits more in the person than in the injury. A large study of surgical patients who had not been using opioids found that 5.9% to 6.5% were still filling opioid prescriptions three to six months after minor or major operations, compared with 0.4% of people who had no surgery. How big the operation was did not predict who kept using. Tobacco use, alcohol and drug use disorders, mood and anxiety disorders, and pain conditions that were there before surgery did.2
That study was about surgery, not back flares, but look at the last item on the list. Back pain before the operation raised the adjusted odds of persistent use to 1.57, the highest of the pain conditions the authors named.2 Someone with a long-standing back problem already carries that predictor before the first pill. Add poor sleep, a stressful stretch or a history of depression and the terrain gets steeper. That is why I would rather your first move for a flare be something other than an opioid.
It was also why I said no. Minimizing that first exposure is worth the effort. I did not want to set myself up for a medicine I might not need down the road.
What should you try first for a back pain flare?
For the first couple of days after my injury, I relied on ibuprofen and acetaminophen and on a short list of devices: TENS, electrical muscle stimulation (EMS), localized vibration from a plate, and infrared light. I think of the devices as distractive tools. They hand the spinal cord competing signals so the pain signal gets less of a hearing. There is nothing woo-woo in it. Each one has a mechanism.
- Ibuprofen plus acetaminophen, on a schedule. In a randomized emergency department trial of 411 adults with acute arm or leg pain, a single dose of ibuprofen 400 mg with acetaminophen 1,000 mg matched three opioid combinations at two hours closely enough that the gap was neither statistically significant nor clinically important.3 It was one dose for limb pain, not back pain, and side effects were not studied. Check with your doctor if you have kidney disease, ulcers or take a blood thinner.
- TENS. Thin, slow fibers carry pain; thick, fast fibers carry touch and pressure. At the spinal cord they compete, which is the gate control theory of pain.4 TENS feeds the fast fibers. Across 381 randomized trials and 24,532 participants, pain scores were lower than with placebo during or immediately after TENS. Reviewers rated that evidence moderate in certainty, saw nothing serious go wrong, and found acute pain responded as well as chronic.5 See TENS for back pain and the home TENS unit for nights and workdays.
- Vibration. Same thick fibers, same gate. Our vibration platform also wakes up the muscles that hold the spine steady.
- Light. Red and near-infrared light acts on cytochrome c oxidase in the mitochondria, raising ATP and lowering inflammatory markers in activated cells. Most of that work is in cells and animals, including traumatic injury models.6 It is promising, not settled. Ours is laser therapy for back pain.
- Movement. Bed rest makes a flare last longer. Short, frequent walks and position changes beat lying still. Our guide to the first 48 hours of a flare lays out the order, and what not to do with a back that has just gone covers the traps.
These tools are part of our physician-directed physiotherapy for back pain.
Why did my pain stay low enough to skip the opioid?
Partly luck of chemistry. After major trauma the brain turns on a descending pain-suppression pathway driven by endorphins, adrenaline and other chemical messengers. This stress-induced analgesia varies enormously from one person to another.7 In my case both endorphins and epinephrine were surging, which is why the pain stayed muted. A back flare at 2 a.m. does not come with that adrenaline surge, which is one more reason not to copy my exact plan.
Does this mean you should refuse an opioid for back pain?
No. This was my own path, and it may not be yours. Some patients need opioids, sometimes for a fracture, sometimes for a nerve that is badly compressed. Pain that is left raw keeps you from walking and sleeping, and a back that cannot move does not recover. Every individual is different, and the right plan starts with the patient who actually walks in, not with an assumption about them.
What I am asking is that declining, or keeping the course as short as possible, gets discussed. Sometimes it works. It is almost never offered.
What if you are already taking opioids for your back?
Then stewardship means something different for you. It is harm reduction for an individual, not a blanket rule in either direction. We help patients who want to come down taper by treating the source of the pain with interventional procedures, such as lumbar radiofrequency ablation for facet pain, while keeping them out of withdrawal. Nobody gets cut off.
Frequently asked questions
How many days of opioids are too many for a back flare?
There is no safe cutoff, but the CDC analysis found the steepest rises in long-term use after day 5 and day 31 of the first episode. If an opioid is needed, the shortest course that gets you moving is the goal.
Can TENS help a back pain flare at home?
Yes, for many people. A review of 381 trials found pain was lower during and right after TENS than with placebo. A home unit lets you use it at night or after work, once a physician has set it up for you.
Is ibuprofen with acetaminophen as strong as an opioid?
For acute limb pain in one emergency department trial, a single dose relieved pain about as well as three opioid combinations at two hours. That trial did not study back pain or repeated doses, so ask your doctor how it fits your situation.
Get a flare plan before the next one
Bring the list of what you have tried, what helped and what did not, including any prescription you were given. We will build the first-line plan around your back and your risks.
12174 Natural Bridge Rd, Suite 301
St. Louis, MO 63044
At DePaul Hospital on Natural Bridge Road, inside the I-270 and I-70 interchange, on the west side of the airport.
Sources
- Shah A, Hayes CJ, Martin BC. Characteristics of initial prescription episodes and likelihood of long-term opioid use: United States, 2006-2015. MMWR Morbidity and Mortality Weekly Report, 2017;66(10):265-269. doi:10.15585/mmwr.mm6610a1
- Brummett CM, Waljee JF, Goesling J et al.. New persistent opioid use after minor and major surgical procedures in US adults. JAMA Surgery, 2017;152(6):e170504. doi:10.1001/jamasurg.2017.0504
- Chang AK, Bijur PE, Esses D, Barnaby DP, Baer J. Effect of a single dose of oral opioid and nonopioid analgesics on acute extremity pain in the emergency department: a randomized clinical trial. JAMA, 2017;318(17):1661-1667. doi:10.1001/jama.2017.16190
- Melzack R, Wall PD. Pain mechanisms: a new theory. Science, 1965;150(3699):971-979. doi:10.1126/science.150.3699.971
- Johnson MI, Paley CA, Jones G, Mulvey MR, Wittkopf PG. Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults: a systematic review and meta-analysis of 381 studies (the meta-TENS study). BMJ Open, 2022;12(2):e051073. doi:10.1136/bmjopen-2021-051073
- Hamblin MR. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics, 2017;4(3):337-361. doi:10.3934/biophy.2017.3.337
- Butler RK, Finn DP. Stress-induced analgesia. Progress in Neurobiology, 2009;88(3):184-202. doi:10.1016/j.pneurobio.2009.04.003






